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Polycystic Ovary Syndrome (PCOS) is a common endocrine and metabolic disorder characterized by excessive androgen secretion and is linked with obesity, insulin resistance and type 2 diabetes, and affects up to 17% of women in reproductive age. We have also demonstrated that women with PCOS have epigenetic and transcriptional changes in skeletal muscle and adipose tissue relevant for development of disease3,4. We have also shown that a single bout of electroacupuncture increases whole-body glucose uptake in overweight and obese women with PCOS by activation of the sympathetic and partly the parasympathetic nervous systems. It is known that a single bout of exercise induce rapid transcriptional and epigenetic changes in skeletal muscle. We have found that a single bout of electroacupuncture, in addition to increase whole-body glucose uptake, also remodels epigenetic and transcriptional changes in adipose tissue and skeletal muscle mimicking a single bout of exercise.
The idea of "experts coming together to produce change" inspired a research project designed to investigate how acupuncture and TCM reproductive specialists approach the treatment of PCOS in their clinics. This presentation reveals these new insights, which includes interesting quantitative data on acupuncture points selection and valuable qualitative reasoning for those choices which will contribute to 1.) demonstrate to colleagues and other healthcare practitioners how acupuncturists treat PCOS in their TCM clinics, and 2.) inform future clinical research by contributing to trial design with aspects of dosage and point selection.
This lecture will share the basis for the development of this condition as well as how it is diagnosed. With a thorough understanding of the multisystem nature of PCOS, a multi-disciplinary team can collaborate to best meet the patient’s immediate needs as well working to reduce long term health risks associated with the condition.
Goals and Outlines
Dr. Perloe earned his medical degree from Pennsylvania State University, Hershey Medical Center, and served his residency in Obstetrics and Gynecology at the University of Wisconsin. Dr. Perloe completed his fellowship in Reproductive Endocrinology and Infertility at the University of Minnesota.
He has extensive experience treating conditions related to infertility including polycystic ovary syndrome, recurrent pregnancy loss, menstrual disorders, fibroids, male factor infertility, endocrine disorders, and other reproductive health problems. His patients have access to the latest in vitro fertilization techniques including fertility preservation, the use of donor eggs, donor sperm, and gestational surrogacy.
Dr. Perloe has served as principal investigator in numerous reproductive health research studies including innovative IVF treatments, ovulation induction, polycystic ovary syndrome, as well as investigational medications for the treatment of male erectile dysfunction. He has served as consultant and a task force member to the Women’s Initiative of the American International Health Association and was active in establishing the first approved endoscopy-training center in the former Soviet Union at the Russian National Institute of Women’s Health.
He has published research in medical journals including Human Reproduction, Fertility and Sterility, Obstetrics & Gynecology, Southern Medical Journal, and the International Journal of Obstetrics and Gynecology.
Sandro is a lecturer and a published researcher in the field of menstrual and reproductive health, Fellow of the ABORM, and one of the Directors at Evidence Based Acupuncture.
Originally from Portugal, Sandro obtained his Licentiate in TCM at the Irish College of TCM in Dublin, followed by a four-week program on acupuncture and moxibustion at the Beijing University of Chinese Medicine.
He completed his MSc in Advanced Oriental Medicine (Research and Practice) at the Northern College of Acupuncture (NCA) – in conjunction with Middlesex University – focusing on acupuncture for polycystic ovary syndrome (PCOS).
Sandro is a lecturer on the online MSc program at the NCA in York, U.K. and he is one of the researchers on the Cochrane Review Groups for acupuncture for dysmenorrhea and for assisted reproductive technology, and Chinese herbal medicine for endometriosis.
He is also the Director for International Membership of the Obstetrical Acupuncture Association (OBAA) and the Social Media Editor of the European Journal of Integrative Medicine. In 2023, Sandro became a Board Member of the Society for Acupuncture Research.
